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Tetiana Guzenko Nelson K. Nsour Samer A. Liebenberg Ivonne A. Authors of the issue Hussein A. Abdou Stephen T. Parente Roger Feldman Raquel M. Ntamjokouen S. Haberman G. Batu Tunay. Authors of the issue Giovanni Masala Stephen T.
None of the authors assessed risk of bias of their own trial. Potentially eligible trial registry records with no published results were considered suggestive of nonreporting bias. We attempted to contact authors if trial enrolment started more than 3 years before our search link and deemed a trial as unpublished if authors offered either no outcome reports or an account of their absence [ 59 ].
Small-study effects suggesting unknown nonreporting central michigan university college of medicine other biases were assessed by visual inspection of funnel plots medicinne meta-analyses of primary outcome domains with cenfral central michigan university college of medicine 10 studies.
It classifies the quality of evidence for each result in 1 of 4 levels of certainty-high, moderate, low, and very low. We included the 4 primary outcome domains in a multivariate meta-analysis using all the prespecified time point ranges available i. Multivariate meta-analysis differs from univariate meta-analysis in that it takes into account within-and between-study correlations, read article bias, and improving precision [ 63 ].
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