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Given the relative lack continue reading significant adverse effects when used for PTSD-related nightmares, research should be conducted for its use in recurrent non-PTSD-related nightmares. Our systematic review agrees with other recent narrative reviews of the use of prazosin lynden family medicine lyndrn PTSD-related nightmares. Already, our review includes 2 recent studies from and that other recent reviews were unable to include, and the significance is that one of these studies reported a negative finding and the lynden family medicine study reported less impressive results than the earlier studies.

Upcoming results from 2 large clinical trials of use of prazosin to treat PTSD symptoms a site VA study of veterans and a mediccine study of soldiers on active dutyexpected to be completed in latewill add greatly to our knowledge. There lynden family medicine several limitations to the present literature review.

One is the relatively small number of studies and total number of patients. There is also heterogeneity of the studies, including the variability of inclusion criteria, psychiatric comorbidities, follow-up periods, outcome measures, and allowance for concurrent medications. A formal meta-analysis would be difficult because of the heterogeneity.

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